Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	105112
Country	China

Category	Surgery
Manuscript Type	Retrospective Study
Article Title	Preoperative interleukin-17a as a predictor of acute pancreatitis after pancreaticoduodenectomy
Manuscript Source	Unsolicited Manuscript
All Author List	Jie Zheng, Jin Wang, Yi-Nong Zhou, Ting-Ting Yu and Wei-Kang Ye
Funding Agency and Grant Number
Corresponding Author	Wei-Kang Ye, Department of Pancreatology, The Quzhou Affiliated Hospital of Wenzhou Medical University ,Quzhou People's Hospital, No. 100 Minjiang Avenue, Kecheng District, Quzhou 324000, Zhejiang Province, China. yu331121@163.com
Key Words	Acute pancreatitis; Pancreaticoduodenectomy; Interleukin-17A; Fluid load; Postoperative pancreatic fistula
Core Tip	Preoperative interleukin-17A (IL-17a) levels independently predict post pancreatectomy acute pancreatitis and related postoperative pancreatic fistula after pancreaticoduodenectomy. Elevated IL-17a reflects inflammatory status, aiding risk stratification and guiding preoperative optimization and postoperative monitoring. Combining IL-17a with fluid management improves predictive accuracy, offering a practical tool for reducing complications.
Citation	Zheng J, Wang J, Zhou YN, Yu TT, Ye WK. Preoperative interleukin-17a as a predictor of acute pancreatitis after pancreaticoduodenectomy. World J Gastrointest Surg 2025; In press

Received	2025-02-12 08:25
Peer-Review Started	2025-02-12 08:25
To Make the First Decision
Return for Revision	2025-03-04 01:36
Revised	2025-03-24 13:10
Second Decision	2025-07-10 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-10 03:47
Articles in Press	2025-07-10 03:47
Publication Fee Transferred	2025-03-25 08:58
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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