Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	105192
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Expression significance of serum APE1-AAbs, PTX-3, and miR-486-3p in patients with colorectal cancer undergoing radical surgery
Manuscript Source	Unsolicited Manuscript
All Author List	Hao Wang and Wei Wang
Funding Agency and Grant Number
Corresponding Author	Wei Wang, Chief Physician, Interventional Medicine Department, The Second Hospital, Shandong University, No. 247 Beiyuan Street, Jinan 250000, Shandong Province, China. xtx442@yeah.net
Key Words	Apurinic/apyrimidinic endonuclease 1 autoantibodies; Peripheral pentraxin-3; MiR-486-3p; Colorectal cancer; Laparoscopic radical surgery; Postoperative recurrence and metastasis; Risk factors; Predictive value
Core Tip	Serum apurinic/apyrimidinic endonuclease 1 autoantibodies, peripheral pentraxin-3, and miR-486-3p levels are higher in colorectal cancer patients with postoperative recurrence and metastasis. These three markers are risk factors for postoperative recurrence and metastasis in colorectal cancer and can be used as predictive biomarkers. The combined detection of these markers has higher predictive value compared to individual tests.
Citation	<p>Wang H, Wang W. Expression significance of serum APE1-AAbs, PTX-3, and miR-486-3p in patients with colorectal cancer undergoing radical surgery. <i>World J Gastrointest Oncol</i> 2025; 17(5): 105192</p>

Received	2025-01-15 01:38
Peer-Review Started	2025-01-15 01:38
To Make the First Decision
Return for Revision	2025-02-13 08:07
Revised	2025-02-17 06:36
Second Decision	2025-03-20 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-03-21 07:54
Articles in Press	2025-03-21 07:54
Publication Fee Transferred
Edit the Manuscript by Language Editor	2025-03-24 02:55
Typeset the Manuscript	2025-04-27 09:29

ISSN	1948-5204 (online)
Open Access	Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com