Publication Name	World Journal of Experimental Medicine
Manuscript ID	105208
Country	India

Category	Infectious Diseases
Manuscript Type	Case Control Study
Article Title	Evaluation of urinary extracellular vesicles and microRNAs to diagnose urogenital tuberculosis
Manuscript Source	Invited Manuscript
All Author List	Parijat Das, Dharmendra K Chaudhary, Richa Mishra and Swasti Tiwari
Funding Agency and Grant Number	Funding Agency Grant Number Indian Council of Medical Research No. Coord/7 (1)/CARE-KD/18-NCD-II
Corresponding Author	Swasti Tiwari, Department of Molecular Medicine and Biotechnology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Mawaiya, Lucknow 226014, Uttar Pradesh, India. tiwari.pgi@gmail.com
Key Words	Tuberculosis; Urine; Extracellular vesicles; MicroRNA; Biomarker
Core Tip	Discovery of new biomarkers from easily attainable bodily fluids is essential for controlling Urogenital tuberculosis (TB), a significant health concern. Urinary extracellular vesicle microRNAs (miRNAs) are exciting as biomarkers given their stability and non-invasive nature. miRNA-155, miRNA-26 and miRNA-29 play a crucial role in mycobacterium TB pathogenesis via regulation of posttranscriptional gene expression and subsequently apoptosis, cellular proliferation, differentiation and several other biological functions governing various facets of innate and acquired immunity. Thus, there is scope for developing miRNA studies using in vitro and in vivo models in TB which would likely lead to new technologies in diagnosis and treatment.
Citation	Das P, Chaudhary DK, Mishra R, Tiwari S. Evaluation of urinary extracellular vesicles and microRNAs to diagnose urogenital tuberculosis. World J Exp Med 2025; In press

Received	2025-01-15 12:30
Peer-Review Started	2025-01-18 08:46
To Make the First Decision
Return for Revision	2025-04-09 01:32
Revised	2025-04-22 12:07
Second Decision	2025-06-19 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-20 01:48
Articles in Press	2025-06-20 01:48
Publication Fee Transferred
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Typeset the Manuscript

ISSN	2220-315x (online)
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