Publication Name	World Journal of Gastroenterology
Manuscript ID	105210
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Predictive value of core-fucosylated low-molecular-weight kininogen levels in patients with liver fibrosis: A prospective study
Manuscript Source	Unsolicited Manuscript
All Author List	Guo-Feng Gao, Jiao Yu, Lin Tong and Dong Jiang
Funding Agency and Grant Number
Corresponding Author	Dong Jiang, MD, Department of Ultrasound, Eastern Hepatobiliary Surgery Hospital, Third affiliated Hospital of Naval Medical University, No. 700 Moyu North Road, Jiading District, Shanghai 200433, China. jiangdong2002317@aliyun.com
Key Words	Core-fucosylated low-molecular-weight kininogen; Liver fibrosis; Cirrhosis; Non-invasive marker; Transient elastography
Core Tip	Liver fibrosis is a common outcome of chronic liver disease, and early detection and diagnosis of liver fibrosis are crucial. Traditional biopsy-based liver fibrosis diagnosis has limitations such as invasiveness. Core-fucosylated low-molecular-weight kininogen (LMWK-Fc) refers to the presence of fucose residues connected to the core of N-linked polysaccharide structures. Changes in LMWK-Fc levels may reflect the evolution of liver fibrosis. This study addressed this gap by studying the potential role of LMWK-Fc levels as a biomarker for predicting liver fibrosis, finding that LMWK-Fc may be a potential biomarker for screening and diagnosing liver fibrosis.
Citation	Gao GF, Yu J, Tong L, Jiang D. Predictive value of core-fucosylated low-molecular-weight kininogen levels in patients with liver fibrosis: A prospective study. World J Gastroenterol 2025; In press

Received	2025-03-12 09:01
Peer-Review Started	2025-03-12 09:01
To Make the First Decision
Return for Revision	2025-03-28 08:27
Revised	2025-06-05 16:01
Second Decision	2025-07-15 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-15 06:58
Articles in Press	2025-07-15 06:58
Publication Fee Transferred	2025-06-07 06:31
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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