Publication Name	World Journal of Cardiology
Manuscript ID	105330
Country	United States

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Retrospective Study
Article Title	Incidence, risk factors and clinical outcomes of pericardial effusion in left ventricular assist device patients
Manuscript Source	Unsolicited Manuscript
All Author List	Muhammad Zubair Khan, Yevgeniy Brailovsky, Mohammad Alfrad Nobel Bhuiyan, Gregary Marhefka, Abu S M Faisal, Adrija Sircar, Parker O'Neill, J Eduardo Rame, Sona Franklin, Muhammad Waqas, Hadia Shah, Indranee Rajapreyar and Rene J Alvarez
Funding Agency and Grant Number
Corresponding Author	Muhammad Zubair Khan, MD, Department of Cardiology, Thomas Jefferson University Jefferson, 111 S 11th St, Philadelphia, PA 19107, United States. muhammad.khan2@jefferson.edu
Key Words	Left ventricular assist device; Pericardial effusion; Cardiac tamponade; Pericardial window; Pericardiocentesis; Risk factors and clinical outcomes of pericardial effusion; Older age; Diabetes; Larger body mass index; Renal failure; malnutrition
Core Tip	Pericardial effusions in patients with left ventricular assist devices (LVADs) can lead to prolonged hospitalization and increased healthcare costs. Risk factors associated with the development of pericardial effusions include: Liver disease, chronic kidney disease (CAD), hypothyroidism, electrolyte derangement, atrial fibrillation, with the highest association found with CAD and percutaneous coronary intervention. While the presence of pericardial effusions did not have significant impact on mortality in our study, further studies are needed to elucidate whether the optimization of these co-morbidities would reduce the incidence of pericardial effusion in patients with LVADs.
Citation	Khan MZ, Brailovsky Y, Bhuiyan MAN, Marhefka G, Faisal ASM, Sircar A, O'Neill P, Rame JE, Franklin S, Waqas M, Shah H, Rajapreyar I, Alvarez RJ. Incidence, risk factors and clinical outcomes of pericardial effusion in left ventricular assist device patients. World J Cardiol 2025; In press

Received	2025-01-21 05:49
Peer-Review Started	2025-01-21 05:49
To Make the First Decision
Return for Revision	2025-04-02 11:18
Revised	2025-04-16 01:24
Second Decision	2025-06-03 02:55
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-03 08:46
Articles in Press	2025-06-03 08:46
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Typeset the Manuscript

ISSN	1949-8462 (online)
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