Publication Name	World Journal of Clinical Cases
Manuscript ID	105415
Country	United States

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Review
Article Title	Red yeast rice with monacolin K for the improvement of hyperlipidemia: A narrative review
Manuscript Source	Invited Manuscript
All Author List	Kevan English
Funding Agency and Grant Number
Corresponding Author	Kevan English, MD, Department of Internal Medicine, University of Nebraska Medical Center College of Medicine, S 42nd & Emile St, Omaha, NE 68198, United States. keenglish@unmc.edu
Key Words	Hyperlipidemia; Red yeast rice; Monacolin K; Low-density lipoprotein; Atherosclerosis; Lovastatin; Coronary artery disease; Statin; Cholesterol
Core Tip	Red yeast rice (RYR) has cholesterol-lowering properties due to its active ingredient, monacolin K (MK), which mainly inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase. It is an excellent option for patients with mild to moderate dyslipidemia and low atherosclerotic cardiovascular disease risk factors who otherwise would not qualify for statin therapy. RYR can also serve as a valuable alternative in patients with statin intolerance or patients who otherwise are against medical treatment. Although effective, it is noteworthy to mention that the quantity of MK in commercial RYR products varies by brand. This article narratively reviews some existing data on RYR in the treatment of mild to moderate dyslipidemia.
Citation	English K. Red yeast rice with monacolin K for the improvement of hyperlipidemia: A narrative review. World J Clin Cases 2025; In press

Received	2025-01-22 10:41
Peer-Review Started	2025-01-22 10:42
To Make the First Decision
Return for Revision	2025-04-16 09:17
Revised	2025-04-19 01:23
Second Decision	2025-06-19 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-19 07:51
Articles in Press	2025-06-19 07:51
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Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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