Publication Name	World Journal of Diabetes
Manuscript ID	105532
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Case Control Study
Article Title	Intraoperative blood perfusion factors in free anterolateral thigh flap repair for diabetic foot ulcers: A retrospective analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Hong-Liang Wu, Huan Huang, Bin-Qi Chen, Jian Xia and Li-Bing Jiang
Funding Agency and Grant Number
Corresponding Author	Li-Bing Jiang, Department of Orthopaedics, The First Hospital of Nanchang, No. 128 Xiangshan North Road, Donghu, Nanchang 330008, Jiangxi Province, China. lijoy1126@163.com
Key Words	Diabetic foot ulcers; Intraoperative blood perfusion; Anterolateral thigh perforator flap; Type 2 diabetes; Surgical outcomes; Vascular health
Core Tip	This study investigates the key factors influencing intraoperative blood perfusion in patients with type 2 diabetes undergoing free anterolateral thigh perforator flap repair for diabetic foot ulcers. We identified that prolonged diabetes duration, elevated glycated hemoglobin, and poor nutritional status significantly impair perfusion. Conversely, higher hemoglobin, albumin, and prealbumin levels were protective. These findings underscore the importance of integrated diabetes management strategies, including metabolic control and nutritional support, to optimize surgical outcomes. Prospective studies are needed to validate these results and refine perioperative care protocols for improved patient outcomes.
Citation	Wu HL, Huang H, Chen BQ, Xia J, Jiang LB. Intraoperative blood perfusion factors in free anterolateral thigh flap repair for diabetic foot ulcers: A retrospective analysis. World J Diabetes 2025; In press

Received	2025-02-18 08:15
Peer-Review Started	2025-02-27 01:00
To Make the First Decision
Return for Revision	2025-03-19 09:14
Revised	2025-04-09 09:30
Second Decision	2025-06-11 03:29
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-04 09:53
Articles in Press	2025-07-04 09:53
Publication Fee Transferred	2025-04-14 01:30
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
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