Publication Name	World Journal of Hepatology
Manuscript ID	105578
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Long-term outcomes of early transjugular intrahepatic portosystemic shunts in patients with acute variceal bleeding and cirrhosis
Manuscript Source	Unsolicited Manuscript
All Author List	Xin Tang, Ju-Bo Liang, Chen Wang, Jia-Li Ma, Rong-Rong Jia, Yu-Gang Wang and Min Shi
Funding Agency and Grant Number	Funding Agency Grant Number Natural Science Foundation of the Science and Technology Commission of Shanghai Municipality No. 23ZR1458300 Key Discipline Project of Shanghai Municipal Health System No. 2024ZDXK0004 Doctoral innovation talent base project for diagnosis and treatment of chronic liver diseases No. RCJD2021B02
Corresponding Author	Min Shi, MD, Professor, Department of Gastroenterology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, No. 1111 Xianxia Road, Changning District, Shanghai 200336, China. sm1790@shtrhospital.com
Key Words	Early transjugular intrahepatic portosystemic shunt; Long-term outcome; Acute variceal bleeding; Cirrhosis; Comorbidities
Core Tip	The long-term outcomes of early transjugular intrahepatic portosystemic shunts (TIPS) for acute variceal bleeding (AVB) remain unclear. This retrospective cohort study analyzed the clinical data of patients with AVB who underwent early TIPS or standard treatment. We found that early TIPS was associated with a lower risk of rebleeding and ascites compared with standard treatment for AVB; however, long-term survival did not improve. Moreover, we identified the presence of comorbidities was associated with survival for AVB.
Citation	Tang X, Liang JB, Wang C, Ma JL, Jia RR, Wang YG, Shi M. Long-term outcomes of early transjugular intrahepatic portosystemic shunts in patients with acute variceal bleeding and cirrhosis. World J Hepatol 2025; In press

Received	2025-02-17 06:39
Peer-Review Started	2025-02-17 06:39
To Make the First Decision
Return for Revision	2025-03-29 10:49
Revised	2025-04-12 04:57
Second Decision	2025-05-16 02:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-16 11:17
Articles in Press	2025-05-16 11:17
Publication Fee Transferred	2025-04-16 12:16
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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