Publication Name	World Journal of Hepatology
Manuscript ID	105582
Country	India

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Gut feeling gone wrong: Tangled relationship between disorders of gut-brain interaction and liver disease
Manuscript Source	Invited Manuscript
All Author List	Manjeet Kumar Goyal, Prerna Goyal, Omesh Goyal and Ajit Sood
Funding Agency and Grant Number
Corresponding Author	Omesh Goyal, Department of Gastroenterology, Dayanand Medical College and Hospital, Tagore Nagar, Ludhiana 141001, Punjab, India. dromeshgoyal@gmail.com
Key Words	Disorders of gut-brain interaction; Liver diseases; Gut-liver axis; Dysbiosis; Cirrhosis; Intestinal permeability; Neuroimmune dysregulation
Core Tip	The review highlights the complex bidirectional relationship between disorders of gut-brain interaction and liver diseases, particularly cirrhosis. It emphasizes shared pathophysiological mechanisms such as gut dysbiosis, increased intestinal permeability, and neuroimmune dysregulation, which exacerbate clinical manifestations and complicate management. The article suggests integrative diagnostic approaches and therapeutic strategies targeting the gut microbiome and neuroimmune pathways to improve patient outcomes.
Citation	Goyal MK, Goyal P, Goyal O, Sood A. Gut feeling gone wrong: Tangled relationship between disorders of gut-brain interaction and liver disease. World J Hepatol 2025; In press

Received	2025-01-30 13:09
Peer-Review Started	2025-01-30 13:09
To Make the First Decision
Return for Revision	2025-03-27 10:31
Revised	2025-04-03 04:24
Second Decision	2025-04-30 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-04-30 05:48
Articles in Press	2025-04-30 05:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
Open Access	Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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