Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	105790
Country	China

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Development and validation of a nomogram for predicting postoperative venous thromboembolism risk in patients with hepatocellular carcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Chun-Rong Chen, Hong-Liang Jin, Qian-Jie Xu, Yu-Liang Yuan, Zu-Hai Hu, Ya Liu and Hai-Ke Lei
Funding Agency and Grant Number
Corresponding Author	Hai-Ke Lei, Associate Professor, PhD, Chongqing Cancer Multi-omics Big Data Application Engineering Research Center, Chongqing University Cancer Hospital, No. 181 Hanyu Road, Shapingba District, Chongqing 400030, China. tohaike@163.com
Key Words	Venous thromboembolism; Hepatocellular carcinoma; Postoperative; Nomogram; Prediction model
Core Tip	This study develops and validates a novel nomogram to predict postoperative venous thromboembolism (VTE) risk in hepatocellular carcinoma patients. Using data from 905 patients, we identified eight independent risk factors for VTE, including Karnofsky Performance Scale score, underlying disease, tumor-node-metastasis stage, chemotherapy, D-dimer, white blood cell count, hemoglobin, and fibrinogen. The nomogram demonstrated excellent discriminative ability (C-index: 0.825 in training, 0.820 in validation cohorts) and calibration. This model can accurately estimate individual VTE risk and aid in targeted anticoagulation strategies for high-risk patients.
Citation	Chen CR, Jin HL, Xu QJ, Yuan YL, Hu ZH, Liu Y, Lei HK. Development and validation of a nomogram for predicting postoperative venous thromboembolism risk in patients with hepatocellular carcinoma. World J Gastrointest Oncol 2025; In press

Received	2025-02-07 04:15
Peer-Review Started	2025-02-07 04:17
To Make the First Decision
Return for Revision	2025-04-08 10:04
Revised	2025-04-14 00:06
Second Decision	2025-05-16 02:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-16 06:54
Articles in Press	2025-05-16 06:54
Publication Fee Transferred	2025-04-15 00:12
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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