Publication Name	World Journal of Hepatology
Manuscript ID	105799
Country	United Kingdom

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Quality of life in hereditary haemochromatosis: Scoping review of symptoms and initial ranking of symptoms by a special interest group
Manuscript Source	Unsolicited Manuscript
All Author List	Muhammad Waqar, Marie Line El Asmar, Debra Gray, Anita Immanuel, Jeremy Shearman and John K Ramage
Funding Agency and Grant Number
Corresponding Author	Marie Line El Asmar, MD, Department of Gastroenterology, Hampshire Hospitals NHS Foundation Trust, Aldermaston Rd, Basingstoke RG24 9NA, Basingstoke RG24 9NA, Hampshire, United Kingdom. marieline.elasmar@hhft.nhs.uk
Key Words	Haemochromatosis; Iron overload; Quality of life; Hyperferritinaemia; Symptoms；Liver
Core Tip	Haemochromatosis presents with diverse symptoms that significantly impact patients’ daily lives. Despite this, no validated tool currently exists to assess quality of life (QoL) in this population. We conducted a scoping review of 47 articles to address this gap, identifying 19 QoL-related issues and symptoms. These were subsequently ranked by a haemochromatosis special interest group based on their importance and relevance. The findings highlight key symptoms affecting haemochromatosis patients’ QoL from literature and professional perspectives and will help inform the development of a standardised questionnaire for evaluating QoL in patients with hereditary haemochromatosis.
Citation	Waqar M, El Asmar ML, Gray D, Immanuel A, Shearman J, Ramage JK. Quality of life in hereditary haemochromatosis: Scoping review of symptoms and initial ranking of symptoms by a special interest group. World J Hepatol 2025; In press

Received	2025-02-07 04:43
Peer-Review Started	2025-02-17 01:21
To Make the First Decision
Return for Revision	2025-04-02 11:19
Revised	2025-04-12 08:05
Second Decision	2025-09-24 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-24 09:35
Articles in Press	2025-09-24 09:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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