Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	105820
Country	India

Category	Infectious Diseases
Manuscript Type	Observational Study
Article Title	Determinants of infection for antibiotic initiation at pediatric emergency admission: A prospective observational study
Manuscript Source	Invited Manuscript
All Author List	Samreen Yusuf, Anil K Goel, Ashish Wasudeo Khobragade, Padma Das, Gudipudi Sai Vamsi Manoj, Anish Kumar Saha, Sai Pratap Reddy, Swasti Keshri and Seema Shah
Funding Agency and Grant Number
Corresponding Author	Anil K Goel, Professor, Department of Pediatrics Emergency Medicine, All India Institute of Medical Sciences, GE Road Raipur, Raipur 492099, Chhattīsgarh, India. akgoel@aiimsraipur.edu.in
Key Words	Antibiotics; Sepsis; Pediatric emergency; Children; Sepsis scoring model in children; Bacterial infection
Core Tip	To diagnose Pediatric sepsis is challenging specially in pediatric emergency medicine (PEM) setting, due to nonspecific signs and symptoms. This can lead to both over and under-utilization of antibiotics. The Children’s Antibiotic Requirement Evaluation Score index is a composite of seven easy-to-determine clinical parameters, i.e., abnormal color, fever, fluid overload, altered sensorium, cellulitis, prior antibiotic use, and C-reactive protein levels, which can guide the emergency physician to use antibiotics rationally during the golden hour of care. This should help to develop a standard and objective approach for the judicious use of antibiotics in PEM setting.
Citation	Yusuf S, Goel AK, Khobragade AW, Das P, Manoj GSV, Saha AK, Reddy SP, Keshri S, Shah S. Determinants of infection for antibiotic initiation at pediatric emergency admission: A prospective observational study. World J Clin Pediatr 2025; In press

Received	2025-02-08 06:25
Peer-Review Started	2025-02-08 06:25
To Make the First Decision
Return for Revision	2025-03-14 09:17
Revised	2025-03-26 06:38
Second Decision	2025-06-09 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-09 06:37
Articles in Press	2025-06-09 06:37
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Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2219-2808 (online)
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