Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	105833
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Functional paraganglioma of the pancreatic head: A case report and review of literature
Manuscript Source	Unsolicited Manuscript
All Author List	Shang-Zheng Luo, Jin-Rui Liu, Tian-Qi Liu and Qing Chen
Funding Agency and Grant Number	Funding Agency Grant Number the Guangxi medical and health care appropriate technology development and popularization and application project S2023034
Corresponding Author	Tian-Qi Liu, MD, Department of General Surgery, Jiangbin Hospital of Guangxi Zhuang Autonomous Region, No. 85 Heti Road, Qingxiu District, Nanning 530021, Guangxi Zhuang Autonomous Region, China. gxljrqt@163.com
Key Words	Pancreatic paraganglioma; Pancreatic tumor; Paraganglioma; Metanephrines; Immunohistochemistry; Case report
Core Tip	We report a rare case of paraganglioma (PGL) of the pancreatic head in a patient with a history of persistent hypertension. Due to atypical clinical presentation and imaging features, it is difficult to differentiate PGL from peripancreatic tumor. PGL may induce persistent clinical symptoms related to hypertension without causing other clinical manifestations that draw the attention of from patients over a long period. In order to improve the diagnostic accuracy of pancreatic PGL, the combination of tests for specific biomarkers (metanephrines/normetanephrines is recommended) and imaging examinations based on individual circumstances is highly recommended. Surgery is still recommended as the mainstay of treatment.
Citation	Luo SZ, Liu JR, Liu TQ, Chen Q. Functional paraganglioma of the pancreatic head: A case report and review of literature. World J Gastrointest Surg 2025; In press

Received	2025-02-08 05:58
Peer-Review Started	2025-02-08 05:58
To Make the First Decision
Return for Revision	2025-03-27 11:45
Revised	2025-04-09 15:50
Second Decision	2025-05-30 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-30 06:36
Articles in Press	2025-05-30 06:36
Publication Fee Transferred	2025-04-15 13:58
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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