Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	105956
Country	China

Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Retrospective Study
Article Title	Diagnostic value of dual-energy computed tomography in irreversible transmural intestinal necrosis in patients with acute occlusive mesenteric ischemia
Manuscript Source	Unsolicited Manuscript
All Author List	Ju-Shun Yang, Zhen-Yu Xu, Fei-Xiang Chen, Mei-Rong Wang, Xiao-Le Fan and Bo-Sheng He
Funding Agency and Grant Number	Funding Agency Grant Number The Project of Nantong City Health Committee MS2023027 and WKZL2018017 The "333" Talent Funding Project of Jiangsu Province BRA2020198 The Project of Jiangsu Provincial Health Commission ZD2021059 The Youth Research Fund of Nantong Municipal Health Commission QNZ2023027
Corresponding Author	Bo-Sheng He, PhD, Department of Radiology, The Second Affiliated Hospital of Nantong University, No. 666 Shengli Road, Nantong 226001, Jiangsu Province, China. boshenghe@126.com
Key Words	Acute mesenteric ischemia; Irreversible transmural intestinal necrosis; Dual-energy computed tomography; Virtual monoenergetic imaging; Iodine concentration
Core Tip	Acute occlusive mesenteric ischemia is an intestinal ischemic injury caused by sudden interruption of intestinal blood supply. If not treated promptly, acute occlusive mesenteric ischemia usually develops into irreversible transmural intestinal necrosis (ITIN). Accurate diagnosis of ITIN is challenging because of its non-specific clinical manifestations. Currently, there is limited research on predicting ITIN using dual energy computed tomography (DECT). We use DECT objective parameters including iodine concentration and virtual monoenergetic imaging to quantify the degree of intestinal wall ischemia, and then evaluate their predictive performance for ITIN. The results demonstrated that DECT quantitative parameters can provide important information about whether ITIN occurs.
Citation	Yang JS, Xu ZY, Chen FX, Wang MR, Fan XL, He BS. Diagnostic value of dual-energy computed tomography in irreversible transmural intestinal necrosis in patients with acute occlusive mesenteric ischemia. World J Gastrointest Surg 2025; In press

Received	2025-02-13 06:06
Peer-Review Started	2025-02-13 06:12
To Make the First Decision
Return for Revision	2025-03-10 11:21
Revised	2025-03-29 13:55
Second Decision	2025-05-29 02:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-29 06:04
Articles in Press	2025-05-29 06:04
Publication Fee Transferred	2025-04-04 13:17
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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