Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	105990
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Ultrasound-guided quadratus lumborum block with general anesthesia for perioperative circulatory stability in colorectal cancer surgery
Manuscript Source	Unsolicited Manuscript
All Author List	Hui-Jie Li, Xi Ban, Jing Li and Su-Qin Huang
Funding Agency and Grant Number
Corresponding Author	Su-Qin Huang, Chief Physician, MD, Department of Anesthesiology, Zhejiang Shuren University Shulan International Medical College Affiliated Shulan (Hangzhou) Hospital, No. 848 Dongxin Road, Hangzhou 310000, Zhejiang Province, China. suqin.huang@shulan.com
Key Words	Quadratus lumborum block; General anesthesia; Colorectal cancer; Perioperative period; Colorectal cancer surgery
Core Tip	This retrospective study demonstrates that ultrasound-guided quadratus lumborum block (QLB) combined with general anesthesia significantly improves perioperative outcomes in colorectal cancer surgery. Compared to general anesthesia alone, QLB reduces stress markers (glucose, lactic acid), enhances renal function (blood urea nitrogen, creatinine), and lowers postoperative pain scores. These findings support the use of QLB as a superior anesthetic strategy to maintain circulatory and metabolic stability, protect organ function, and improve recovery. QLB is especially beneficial for patients with renal vulnerability, high stress reactivity, or low pain tolerance, offering safer and more effective perioperative management.
Citation	Li HJ, Ban X, Li J, Huang SQ. Ultrasound-guided quadratus lumborum block with general anesthesia for perioperative circulatory stability in colorectal cancer surgery. World J Gastrointest Surg 2025; In press

Received	2025-04-30 08:46
Peer-Review Started	2025-04-30 08:46
To Make the First Decision
Return for Revision	2025-05-17 03:40
Revised	2025-05-29 11:38
Second Decision	2025-06-23 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-23 06:32
Articles in Press	2025-06-23 06:32
Publication Fee Transferred	2025-06-03 07:18
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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