Publication Name	World Journal of Psychiatry
Manuscript ID	105992
Country	China

Category	Psychiatry
Manuscript Type	Retrospective Study
Article Title	Neuropsychiatric symptoms in the context of hemodynamic disruption during septic shock
Manuscript Source	Unsolicited Manuscript
All Author List	Hai-Ning Li, Jia-Lin Wang and Wei Chen
Funding Agency and Grant Number
Corresponding Author	Wei Chen, Department of Critical Care Medicine, Shenyang Tenth People's Hospital, No.11 Beihai Street, Dandong District, Shenyang 110044, Liaoning Province, China. cwei7636@163.com
Key Words	Septic shock; Hemodynamics; Neuropsychiatric Symptoms; Delirium
Core Tip	Septic shock induces severe hemodynamic disturbances, which are closely linked to neuropsychiatric symptoms such as delirium, anxiety, depression, and post-traumatic stress disorder. This study highlights the impact of impaired cerebral perfusion, inflammatory cascades, and neurotransmitter imbalances on cognitive function. Key hemodynamic markers, including low cardiac output, elevated lactate, and reduced mean arterial pressure, significantly correlate with neuropsychiatric symptom severity. Early hemodynamic optimization and inflammation control may mitigate these complications and improve patient outcomes. These findings provide insights into the pathophysiological mechanisms underlying neuropsychiatric manifestations in septic shock, emphasizing the need for targeted interventions in critically ill patients.
Citation	Li HN, Wang JL, Chen W. Neuropsychiatric symptoms in the context of hemodynamic disruption during septic shock. World J Psychiatry 2025; In press

Received	2025-03-05 08:21
Peer-Review Started	2025-03-05 08:22
To Make the First Decision
Return for Revision	2025-03-20 02:49
Revised	2025-04-11 15:26
Second Decision	2025-05-12 10:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-19 10:26
Articles in Press	2025-05-19 10:26
Publication Fee Transferred	2025-04-18 09:27
Edit the Manuscript by Language Editor	2025-05-30 03:33
Typeset the Manuscript

ISSN	2220-3206 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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