Publication Name	World Journal of Orthopedics
Manuscript ID	106041
Country	China

Category	Orthopedics
Manuscript Type	Retrospective Study
Article Title	Treatment of lumbar tuberculosis with minimally invasive anterior lesion clearance combined with posterior fixation
Manuscript Source	Unsolicited Manuscript
All Author List	Fei-Fei Pu, Xiang-Lin Peng, Fang-Zheng Zhou, Xiao-Long Zhao, Ling Yang, Jun-Qing Cao, Liu Wei, Jing Feng and Ping Xia
Funding Agency and Grant Number	Funding Agency Grant Number Medical Research Project of Wuhan Municipal Health Commission WX21M02
Corresponding Author	Ping Xia, Chief Physician, Director, MD, PhD, Department of Orthopedics, Wuhan Fourth Hospital (Puai Hospital), No. 215 Zhongshan Road, Wuhan 430022, Hubei Province, China. xiapingfm@163.com
Key Words	Lumbar tuberculosis; Pedicle screw fixation; Minimally surgery; Lesion removal
Core Tip	This study demonstrates that posterior pedicle screw fixation combined with minimally invasive anterior lesion clearance and bone graft fusion is an effective and safe treatment for lumbar tuberculosis. Clinical outcomes showed significant improvements in Cobb angle, pain relief (visual analog scale score), and neurological function (Frankel classification), with a high rate of first-stage wound healing (22/24 cases) and successful bone fusion (average: 5.2 months). While complications were rare (one case of incisional sinus tract and one recurrence), the combined approach offers minimally invasive advantages, including reduced soft tissue damage, faster recovery, and stable spinal reconstruction. These findings support its use as a viable surgical strategy for lumbar tuberculosis, balancing radical debridement, deformity correction, and functional restoration while minimizing morbidity. Further studies with larger cohorts are warranted to validate long-term efficacy.
Citation	Pu FF, Peng XL, Zhou FZ, Zhao XL, Yang L, Cao JQ, Wei L, Feng J, Xia P. Treatment of lumbar tuberculosis with minimally invasive anterior lesion clearance combined with posterior fixation. World J Orthop 2025; In press

Received	2025-02-17 09:27
Peer-Review Started	2025-02-17 09:27
To Make the First Decision
Return for Revision	2025-04-01 06:39
Revised	2025-04-13 11:03
Second Decision	2025-06-13 02:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-13 09:09
Articles in Press	2025-06-13 09:09
Publication Fee Transferred	2025-04-14 08:41
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-5836 (online)
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