Publication Name	World Journal of Psychiatry
Manuscript ID	106062
Country	Japan

Category	Psychiatry
Manuscript Type	Editorial
Article Title	Gut-skin-brain axis in people suffering from sepsis with acute skin failure
Manuscript Source	Invited Manuscript
All Author List	Takahiko Nagamine
Funding Agency and Grant Number
Corresponding Author	Takahiko Nagamine, MD, PhD, Psychiatric Internal Medicine, Sunlight Brain Research Center, 4-13-18 Jiyugaoka, Hofu 7470066, Yamaguchi, Japan. anagamine@yahoo.co.jp
Key Words	Acute skin failure; Anxiety; Gut-skin-brain axis; Insomnia; Sepsis
Core Tip	Acute skin failure tends to cause insomnia and anxiety. The skin, along with the gut, is an organ that functions as a barrier, forming the gut-skin-brain axis. The gut-skin-brain axis is a bidirectional relationship mediated by the immune system, hormones, and the autonomic nervous system. Studying the gut-skin-brain axis holds immense promise for understanding mental illness due to the intricate and bidirectional communication network it represents. In essence, the gut-skin-brain axis provides a framework for understanding how interactions between the gut, skin, and brain can influence mental health, opening new avenues for prevention and treatment.
Citation	Nagamine T. Gut-skin-brain axis in people suffering from sepsis with acute skin failure. World J Psychiatry 2025; In press

Received	2025-02-17 09:33
Peer-Review Started	2025-02-17 09:33
To Make the First Decision
Return for Revision	2025-03-19 07:49
Revised	2025-03-20 05:05
Second Decision	2025-04-14 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-04-14 06:59
Articles in Press	2025-04-14 06:59
Publication Fee Transferred
Edit the Manuscript by Language Editor	2025-04-20 22:56
Typeset the Manuscript

ISSN	2220-3206 (online)
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