Publication Name	World Journal of Methodology
Manuscript ID	106277
Country	United States

Category	Medicine, General & Internal
Manuscript Type	Meta-Analysis
Article Title	Association of neutrophil-lymphocyte ratio with all-cause and cardiovascular mortality in peritoneal dialysis patients: A systematic review and meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Nanush Damarlapally, Roopeessh Vempati, Denise Mourad, Srivatsa Surya Vasudevan, Gaurav Mathur, Afrasayab Khan, Prathibha Banda, Harshavardhan Polamarasetty, Shaylika Chauhan, Nirmala Manjappachar, Talha Bhatti and Rupak Desai
Funding Agency and Grant Number
Corresponding Author	Shaylika Chauhan, Assistant Professor, FACP, MD, Department of Internal Medicine, Geisinger Health System, 1000 E Mountain Blvd, Wikes-Barre, PA 18707, United States. drshaylikachauhan@gmail.com
Key Words	Neutrophil-to-lymphocyte ratio; Peritoneal dialysis; All-cause mortality; Cardiovascular mortality; End stage renal disease; Chronic renal failure; Mortality; Dialysis; Elderly; Cardiac arrest
Core Tip	Inflammation plays a silent but an important role in patients undergoing peritoneal dialysis (PD). This meta-analysis reveals that a simple, and inexpensive blood marker such as elevated neutrophil-to-lymphocyte ratio (NLR) (NLR > 3) can significantly predict all-cause and cardiovascular mortality in this vulnerable group. With data from over 4300 patients, our study also identified age as a key confounder, urging clinicians to interpret NLR levels with caution in older adults. These findings position NLR as a powerful, accessible tool for early risk detection and tailored intervention in PD care.
Citation	Damarlapally N, Vempati R, Mourad D, Vasudevan SS, Mathur G, Khan A, Banda P, Polamarasetty H, Chauhan S, Manjappachar N, Bhatti T, Desai R. Association of neutrophil-lymphocyte ratio with all-cause and cardiovascular mortality in peritoneal dialysis patients: A systematic review and meta-analysis. World J Methodol 2025; In press

Received	2025-02-21 07:02
Peer-Review Started	2025-02-26 05:40
To Make the First Decision
Return for Revision	2025-04-08 06:08
Revised	2025-05-06 08:08
Second Decision	2025-07-04 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-04 08:43
Articles in Press	2025-07-04 08:43
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ISSN	2222-0682 (online)
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