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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 106297
Country China
Category Medicine, General & Internal
Manuscript Type Retrospective Study
Article Title Comparative impact of antiviral therapies on postoperative recurrence risk in patients with hepatitis B virus-related hepatocellular carcinoma  
Manuscript Source Unsolicited Manuscript
All Author List Hua-Mei Liu, Xin Zhang, Hang-Ying Huang, Jia-Min Sun and Qing-Dong Tong
Funding Agency and Grant Number
Corresponding Author Qing-Dong Tong, Chief Physician, MD, Department of Infectious Diseases, The Second Hospital of Longyan, No. 153 Dongxing Road, Xinluo District, Longyan 364000, Fujian Province, China. 13616906527@163.com
Key Words Hepatitis B virus; Hepatectomy; Hepatocellular carcinoma; Tenofovir disoproxil fumarate; Entecavir; Relapse
Core Tip This study compared the recurrence rate of hepatocellular carcinoma (HCC) after radical resection of HCC in patients treated with entecavir (ETV) or tenofovir fumarate (TDF) after propensity score matching. Results revealed that HCC recurrence was observed in 33 (66.0%) patients in the ETV group and 21 (42.0%) in the TDF group, and the risk for HCC recurrence was lower in the TDF group than in the ETV group (P = 0.016). The cumulative recurrence rates of HCC at 1, 3, and 5 years in the ETV and TDF groups were 26.0%, 58.0%, and 66.0%, and 18.0%, 38.0%, and 42.0%, respectively (P = 0.045).  
Citation Liu HM, Zhang X, Huang HY, Sun JM, Tong QD. Comparative impact of antiviral therapies on postoperative recurrence risk in patients with hepatitis B virus-related hepatocellular carcinoma. World J Gastrointest Oncol 2025; In press
Received
2025-03-21 09:54
Peer-Review Started
2025-03-21 09:55
To Make the First Decision
Return for Revision
2025-04-08 12:54
Revised
2025-04-15 04:11
Second Decision
2025-07-30 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-07-30 07:11
Articles in Press
2025-07-30 07:11
Publication Fee Transferred
2025-04-23 02:02
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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