Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	106685
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Retrospective investigation of risk factors for pancreatic fistula development after pancreaticoduodenectomy
Manuscript Source	Unsolicited Manuscript
All Author List	Lei Yao, Kai Zhu, Jian Yuan, Zhao-Xia Luo and Wen-Guang Huang
Funding Agency and Grant Number
Corresponding Author	Lei Yao, Department of General Surgery, China Resources and WISCO General Hospital, No. 209 Metallurgical Avenue, Qingshan District, Wuhan 430080, Hubei Province, China. 15871707870@163.com
Key Words	Risk prediction model; Risk factor; Pancreatic fistula; Pancreaticoduodenectomy; Predictive model
Core Tip	Postoperative pancreatic fistula remains a significant challenge after pancreaticoduodenectomy, impacting patient outcomes and healthcare costs. Recent advancements in diagnostic criteria have refined our understanding of risk factors, including the main pancreatic duct index, pancreatic computed tomography value, and tumor characteristics. Integrating these factors into predictive models helps identify high-risk patients early, allowing for targeted interventions and improved surgical outcomes. Adopting standardized grading systems ensures consistent reporting and enhances clinical decision-making. This study underscores the importance of combining clinical, radiological, and pathological data in postoperative pancreatic fistula risk assessment, ultimately guiding more personalized perioperative care strategies and reducing complication rates.
Citation	Yao L, Zhu K, Yuan J, Luo ZX, Huang WG. Retrospective investigation of risk factors for pancreatic fistula development after pancreaticoduodenectomy. World J Gastrointest Surg 2025; In press

Received	2025-04-22 09:37
Peer-Review Started	2025-04-22 09:38
To Make the First Decision
Return for Revision	2025-05-15 01:53
Revised	2025-06-04 08:23
Second Decision	2025-09-03 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-03 07:49
Articles in Press	2025-09-03 07:49
Publication Fee Transferred	2025-07-02 07:03
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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