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Articles in Press
6/16/2025 9:05:02 AM | Browse: 26 | Download: 0
| Category |
Oncology |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Adult pancreatoblastoma: Systematic review of the literature and case report of a young adult patient
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jacob T Harris, Steve Gurley and Erkut Borazanci |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Honor Health Foundation, Michael and Mary Ellen Francis; and the Seena Magowitz Foundation |
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| Corresponding Author |
Jacob T Harris, MD, Internal Medicine, HonorHealth Thompson Peak Medical Center, 7400 E Thompson Peak Parkway, Scottsdale, AZ 85255, United States. jacharris@honorhealth.com |
| Key Words |
Adult pancreatoblastoma; Pancreatoblastoma genetic features; Pancreatoblastoma histological features; Pancreatoblastoma treatment; Pancreatoblastoma physical features; Adult pancreatoblastoma case report; Adult pancreatoblastoma systematic review |
| Core Tip |
Pancreatoblastoma is exceedingly rare in the adolescent/adult population. This is a systematic review of all the 89 available cases in the literature as well as a case presentation. Notable results of this study include: (1) Common histologic features of acinar groups, squamous corpuscles/nests, cytokeratin, chromogranin, trypsin, chymotrypsin, and synaptophysin; (2) Common genetic features of adenomatous polyposis coli, B-cell lymphoma/leukemia 10, catenin beta 1, and Wnt/beta-catenin mutations; and (3) Chemotherapeutic regimens including cisplatin, carboplatin, doxorubicin, 5 fluorouracil, mitomycin, bleomycin, gemcitabine, and vindesine. Future therapies should focus on targeting the Wnt pathway. |
| Citation |
Harris JT, Gurley S, Borazanci E. Adult pancreatoblastoma: Systematic review of the literature and case report of a young adult patient. World J Gastrointest Oncol 2025; In press |
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Received |
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2025-03-05 11:25 |
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Peer-Review Started |
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2025-03-05 11:25 |
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To Make the First Decision |
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Return for Revision |
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2025-04-16 10:19 |
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Revised |
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2025-04-30 18:39 |
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Second Decision |
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2025-06-16 02:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-06-16 09:05 |
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Articles in Press |
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2025-06-16 09:05 |
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Publication Fee Transferred |
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2025-05-14 03:45 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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