Publication Name	World Journal of Stem Cells
Manuscript ID	106856
Country	India

Category	Cell Biology
Manuscript Type	Letter to the Editor
Article Title	First-ever stem cell therapy restores insulin independence in type 1 diabetes: A medical milestone
Manuscript Source	Unsolicited Manuscript
All Author List	Dinesh Kumar, Rajni Tanwar and Vrinda Gupta
Funding Agency and Grant Number
Corresponding Author	Dinesh Kumar, Associate Professor, School of Pharmacy, Desh Bhagat University, Amloh Road, Mandi Gobindgarh 147301, Punjab, India. dineshpotlia123@gmail.com
Key Words	Stem cell therapy; Diabetes; Type 1 diabetes; Type 2 diabetes; Insulin production; Regenerative medicine; Induced pluripotent stem cells; Clinical trials; Pancreatic regeneration; Autoimmune disease
Core Tip	Stem cell therapy is emerging as a promising approach for type 1 diabetes by regenerating insulin-producing beta cells. This article highlights the first reported case of insulin independence using autologous induced pluripotent stem cell-derived islet-like cells and critically discusses clinical trial trends, ethical concerns, and safety considerations. While not yet a cure, these developments offer a glimpse into the future of regenerative diabetes therapy.
Citation	Kumar D, Tanwar R, Gupta V. First-ever stem cell therapy restores insulin independence in type 1 diabetes: A medical milestone. World J Stem Cells 2025; In press

Received	2025-03-11 10:15
Peer-Review Started	2025-03-13 07:28
To Make the First Decision
Return for Revision	2025-05-13 12:23
Revised	2025-05-14 19:17
Second Decision	2025-06-23 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-23 11:15
Articles in Press	2025-06-23 11:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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