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4/14/2025 6:38:57 AM | Browse: 48 | Download: 0
Publication Name World Journal of Diabetes
Manuscript ID 106884
Country China
Category Pediatrics
Manuscript Type Letter to the Editor
Article Title Immune biomarkers as early indicators of renal damage in type 1 diabetic children: A step toward translational medicine
Manuscript Source Invited Manuscript
All Author List Jian-Wen Fan, Su-Yi Xu, Jun Wu and Yong-Wei Yu
Funding Agency and Grant Number
Corresponding Author Yong-Wei Yu, Department of Intensive Care Unit, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Shangcheng District, Hangzhou 310003, Zhejiang Province, China. yuyongwei@zju.edu.cn
Key Words Type 1 diabetes; Immune biomarkers; Renal damage; Risk stratification; Translational medicine
Core Tip Immune biomarkers play a crucial role in the early detection of renal damage in children with type 1 diabetes. This letter highlights the need for integrating immune indicators into a dynamic risk stratification model, combining metabolic and genetic factors for improved predictive accuracy. Additionally, we emphasize the importance of longitudinal studies to assess biomarker temporal dynamics and explore immunomodulatory strategies for early intervention. Advancing these approaches could enhance the clinical utility of immune biomarkers, facilitating their translation into routine diagnostics and personalized treatment strategies for diabetic nephropathy prevention.
Citation Fan JW, Xu SY, Wu J, Yu YW. Immune biomarkers as early indicators of renal damage in type 1 diabetic children: A step toward translational medicine. World J Diabetes 2025; In press
Received
2025-03-10 09:12
Peer-Review Started
2025-03-11 07:48
To Make the First Decision
Return for Revision
2025-03-27 09:26
Revised
2025-04-04 15:45
Second Decision
2025-04-14 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-04-14 06:38
Articles in Press
2025-04-14 06:38
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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