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Publication Name World Journal of Transplantation
Manuscript ID 106938
Country Mexico
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Risk factors for autoimmune liver disease recurrence after liver transplantation
Manuscript Source Invited Manuscript
All Author List Moisés Salgado-de la Mora, Osvely Mendez-Guerrero, Aldo Torre, Mario Vilatoba, Graciela E Castro Narro, Mario Isaac Lumbreras Márquez and Nalu Navarro-Alvarez
Funding Agency and Grant Number
Corresponding Author Nalu Navarro-Alvarez, Assistant Professor, MD, PhD, Department of Gastroenterology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, 15 Vasco de Quiroga, Mexico City 14080, Mexico. nalu.navarroa@incmnsz.mx
Key Words Autoimmune hepatitis; Primary biliary cholangitis; Primary sclerosing cholangitis; Liver disease; Liver transplantation
Core Tip Autoimmune liver disease (AILD) recurrence after liver transplantation remains a significant concern, yet its predictive factors are not well established. This retrospective cohort study identified higher pre-transplant Child-Pugh and model for end-stage liver disease score, along with alanine aminotransferase > 2 times the upper limit of normal, as significant risk factors for recurrence. Using logistic regression models, we demonstrated a moderate predictive ability for recurrence, though no single model outperformed the others. These findings provide insights into risk stratification, potentially aiding in post-transplant management and surveillance strategies for AILD patients.
Citation Salgado-de la Mora M, Mendez-Guerrero O, Torre A, Vilatoba M, Castro Narro GE, Lumbreras Márquez MI, Navarro-Alvarez N. Risk factors for autoimmune liver disease recurrence after liver transplantation. World J Transplant 2025; In press
Received
2025-03-11 02:16
Peer-Review Started
2025-03-11 02:16
To Make the First Decision
Return for Revision
2025-05-09 12:47
Revised
2025-05-21 04:03
Second Decision
2025-07-25 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-07-25 08:45
Articles in Press
2025-07-25 08:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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