Publication Name	World Journal of Clinical Oncology
Manuscript ID	107009
Country	China

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Survival benefits of concurrent immune checkpoint inhibitor and radiotherapy in non-small cell lung cancer with brain metastases
Manuscript Source	Invited Manuscript
All Author List	Xue-Jie Liu, Heng Ge and Chun-Luan Yuan
Funding Agency and Grant Number
Corresponding Author	Chun-Luan Yuan, Department of Oncology, The First People’s Hospital of Lianyungang, No. 6 Zhenhua Road, Lianyungang 222016, Jiangsu Province, China. zhaoqin0909@sina.com
Key Words	Non-small cell lung cancer; Brain metastasis; Immune checkpoint inhibitor; Radiotherapy; Survival; Sequence
Core Tip	Immunotherapy can combine with radiotherapy to destroy cancer, either use radiotherapy and immunotherapy at the same time, or treated with radiotherapy first and then use immunotherapy. However, what is the better sequence of radiotherapy and immunotherapy for non-small cell lung cancer patients with brain metastasis? In the present study, we collected the data of non-small cell lung cancer patients with brain metastasis, we found some patients received radiotherapy at first, and then treated with immunotherapy. Those patients did not live as long as patients treated with radiotherapy and immunotherapy at the same time.
Citation	Liu XJ, Ge H, Yuan CL. Survival benefits of concurrent immune checkpoint inhibitor and radiotherapy in non-small cell lung cancer with brain metastases. World J Clin Oncol 2025; In press

Received	2025-03-14 06:49
Peer-Review Started	2025-03-14 06:49
To Make the First Decision
Return for Revision	2025-04-23 11:49
Revised	2025-05-07 16:26
Second Decision	2025-06-25 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-26 04:18
Articles in Press	2025-06-26 04:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
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