Publication Name	World Journal of Clinical Cases
Manuscript ID	107096
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Acinar cystic transformation of the pancreas: A rare case report
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Ying Zhong, Zi-Jian Liang, Meng-Long Lan, Xiao-Gang Xu, Li Yuan and Ji-Xiao Zeng
Funding Agency and Grant Number
Corresponding Author	Ji-Xiao Zeng, MD, PhD, Professor, Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, No. 318 Renmin Road, Guangzhou 510623, Guangdong Province, China. zengjixiao@163.com
Key Words	Acinar cystic transformation; Acinar cystic transformation of the pancreas; Acinar cell cystadenoma; Pancreatic cystic tumors; Pancreatic neoplasm; Cystadenoma; Case report
Core Tip	Acinar cystic transformation of the pancreas (ACT) is a rare non-neoplastic transformation of the pancreas, more rarely seen in children. Diagnosis is based on histological findings and therapy should be individualized. We report a rare case of a female child undergoing tumor reduction surgery. ACT is a heterogeneous entity, including a wide spectrum of lesions with different potential etiopathogenetic. Since the clinical course is almost invariably benign, it do not support upfront surgical resection unless for symptomatic lesions. So we draw a conclusion that ACT is a slow-growing benign tumor. The principle of treatment is to follow up the child closely rather than to undergo overly aggressive surgery when imaging and cytological results are mutually supportive.
Citation	Zhong XY, Liang ZJ, Lan ML, Xu XG, Yuan L, Zeng JX. Acinar cystic transformation of the pancreas: A rare case report. World J Clin Cases 2025; In press

Received	2025-03-16 04:56
Peer-Review Started	2025-03-16 04:56
To Make the First Decision
Return for Revision	2025-03-25 03:21
Revised	2025-04-05 16:06
Second Decision	2025-05-08 02:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-08 12:49
Articles in Press	2025-05-08 12:49
Publication Fee Transferred	2025-04-11 09:10
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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