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Publication Name World Journal of Gastrointestinal Endoscopy
Manuscript ID 107142
Country United States
Category Gastroenterology & Hepatology
Manuscript Type Meta-Analysis
Article Title Advancing hemostasis: A meta-analysis of novel vs conventional endoscopic therapies for non variceal upper gastrointestinal bleeding
Manuscript Source Unsolicited Manuscript
All Author List Shivangini Duggal, Ishana Kalra, Keisha Kalra and Vicky Bhagat
Funding Agency and Grant Number
Corresponding Author Shivangini Duggal, MD, Internal Medicine, Texas Tech University Health Sciences Center, 5001 El Paso Dr, El Paso, TX 79905, United States. sduggal@ttuhsc.edu
Key Words Hemostatic methods; Non-variceal upper gastrointestinal bleeding; Over-the-scope-clips; Conventional methods; hemostatic spray
Core Tip This systematic review and network meta-analysis compares the efficacy of novel hemostatic interventions-over-the-scope clips (OTSC) and hemostatic powders (HP)-to conventional endoscopic therapy computed tomography (CT) for non variceal upper gastrointestinal bleeding (NVUGIB). OTSC demonstrated superior efficacy in reducing 30-day and short-term rebleeding rates, ranking as the most effective intervention. HP provided a moderate benefit but did not surpass CT. These findings support OTSC as a first-line treatment for high-risk NVUGIB, while HP remains a viable adjunct.
Citation Duggal S, Kalra I, Kalra K, Bhagat V. Advancing hemostasis: A meta-analysis of novel vs conventional endoscopic therapies for non variceal upper gastrointestinal bleeding. World J Gastrointest Endosc 2025; In press
Received
2025-03-17 03:54
Peer-Review Started
2025-03-24 00:12
To Make the First Decision
Return for Revision
2025-04-02 11:21
Revised
2025-04-07 11:30
Second Decision
2025-05-08 02:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-05-08 12:52
Articles in Press
2025-05-08 12:52
Publication Fee Transferred
2025-04-08 02:59
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5190 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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