Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	107142
Country	United States

Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	Advancing hemostasis: A meta-analysis of novel vs conventional endoscopic therapies for non variceal upper gastrointestinal bleeding
Manuscript Source	Unsolicited Manuscript
All Author List	Shivangini Duggal, Ishana Kalra, Keisha Kalra and Vicky Bhagat
Funding Agency and Grant Number
Corresponding Author	Shivangini Duggal, MD, Internal Medicine, Texas Tech University Health Sciences Center, 5001 El Paso Dr, El Paso, TX 79905, United States. sduggal@ttuhsc.edu
Key Words	Hemostatic methods; Non-variceal upper gastrointestinal bleeding; Over-the-scope-clips; Conventional methods; hemostatic spray
Core Tip	This systematic review and network meta-analysis compares the efficacy of novel hemostatic interventions-over-the-scope clips (OTSC) and hemostatic powders (HP)-to conventional endoscopic therapy computed tomography (CT) for non variceal upper gastrointestinal bleeding (NVUGIB). OTSC demonstrated superior efficacy in reducing 30-day and short-term rebleeding rates, ranking as the most effective intervention. HP provided a moderate benefit but did not surpass CT. These findings support OTSC as a first-line treatment for high-risk NVUGIB, while HP remains a viable adjunct.
Citation	Duggal S, Kalra I, Kalra K, Bhagat V. Advancing hemostasis: A meta-analysis of novel vs conventional endoscopic therapies for non variceal upper gastrointestinal bleeding. World J Gastrointest Endosc 2025; In press

Received	2025-03-17 03:54
Peer-Review Started	2025-03-24 00:12
To Make the First Decision
Return for Revision	2025-04-02 11:21
Revised	2025-04-07 11:30
Second Decision	2025-05-08 02:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-08 12:52
Articles in Press	2025-05-08 12:52
Publication Fee Transferred	2025-04-08 02:59
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5190 (online)
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