| Category |
Infectious Diseases |
| Manuscript Type |
Retrospective Study |
| Article Title |
Burden of multi-drug-resistant organisms in a tertiary healthcare institute in North India: Implications for regional public health
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Harshita Singh, Ananya Ashwairya Patel, Pradeep Pandy, Balram Ji Omar, Amber Prasad, Vanya Singh, Prakhar Sharma, Mukesh Bairwa, Rakesh Kumar Sihag, Ashutosh Tiwari, Deepak Rajput, Manish Kulshrestha, Sandeep Saini, Ajay Kumar, Bhaskar Sarkar, Bhanu Duggal, Ankit Agarwal, Nidhi Kaeley, Gaurav Dhingra, Prakash Mahala, Vishnu Yesodharan, Himanshu Chauhan, Deepa Kumari, Suman Choudhary, Ashok K Sharma, Rakhi Yadav and Prasan Kumar Panda |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Prasan Kumar Panda, Additional Professor, Division of Internal Medicine, All India Institute of Medical Sciences, College Block, Rishikesh 249203, India. motherprasanna@rediffmail.com |
| Key Words |
Multi-drug resistance; Antimicrobial stewardship; Infection control; Klebsiella pneumoniae; Public health |
| Core Tip |
The study assesses the burden of multidrug-resistant organisms (MDROs) in All India Institute of Medical Sciences Rishikesh from May 2021 to February 2024 except 2022. Klebsiella pneumoniae (30.6%) was the most common MDRO, with urine as the predominant sample type (51.0%). The highest burden was observed in the General Medicine and Surgery Departments, with significant quarterly variations (P < 0.001). Uttar Pradesh and Uttarakhand contributed the most cases, particularly from Bijnor and Haridwar districts. There was post-corona virus disease surge of MDROs and 1/4th died. Strengthening antimicrobial stewardship and infection control, especially in high-burden departments and regions, is crucial to curb antimicrobial resistance. |
| Citation |
Singh H, Patel AA, Pandy P, Omar BJ, Prasad A, Singh V, Sharma P, Bairwa M, Sihag RK, Tiwari A, Rajput D, Kulshrestha M, Saini S, Kumar A, Sarkar B, Duggal V, Agarwal A, Kaeley N, Dhingra G, Mahala P, Yesodharan V, Chauhan H, Kumari D, Chaudhary S, Sharma AK, Yadav R, Panda PK. The burden of multi-drug-resistant organisms in a tertiary healthcare institute in North India: Implications for regional public health. World J Exp Med 2025; In press |
| ISSN |
2220-315x (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
