BPG is committed to discovery and dissemination of knowledge
Articles in Press
6/25/2025 9:00:18 AM | Browse: 34 | Download: 0
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Challenges of Klebsiella pneumoniae infections post-liver transplantation: Insights and future directions
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Jian Li and Wei Wang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Second Batch of Social Development Science and Technology Program Projects of Taizhou Science and Technology Bureau in 2023 |
24ywb80 |
|
| Corresponding Author |
Wei Wang, Associate Professor, MD, Department of Interventional Oncology, Municipal Hospital Affiliated to Taizhou University, No. 381-1 Zhongshan East Road, Jiaojiang District, Taizhou 318000, Zhejiang Province, China. westernfox000@163.com |
| Key Words |
Antimicrobial resistance; Host-pathogen interactions; Immunomodulatory therapies; Klebsiella pneumoniae; Liver transplantation; Microbial genomics; Polymyxin B; Pre-transplant surveillance; Therapeutic strategies |
| Core Tip |
Klebsiella pneumoniae infections are a major challenge in liver transplantation recipients, particularly due to carbapenem-resistant strains. Effective management requires addressing key risk factors, including pre-transplant colonization and immune dysregulation. Advanced diagnostics like genomic profiling and resistome analysis can enhance understanding of resistance and virulence mechanisms. Optimizing treatment regimens, such as polymyxin B and ceftazidime/avibactam, and developing novel therapeutics targeting specific resistance mechanisms are critical. Routine surveillance and international collaboration can further improve infection control strategies, ensuring better outcomes for this vulnerable population. Integrating microbiology, immunology, and pharmacology advances is essential for transforming liver transplantation infection care. |
| Citation |
Li J, Wang W. Challenges of Klebsiella pneumoniae infections post-liver transplantation: Insights and future directions. World J Hepatol 2025; In press |
 |
Received |
|
2025-03-18 13:28 |
|
Peer-Review Started |
|
2025-03-19 09:14 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2025-04-03 08:59 |
|
Revised |
|
2025-04-13 12:19 |
|
Second Decision |
|
2025-06-25 02:46 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2025-06-25 09:00 |
|
Articles in Press |
|
2025-06-25 09:00 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
|
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
