Publication Name	World Journal of Gastroenterology
Manuscript ID	107260
Country	Serbia

Category	Immunology
Manuscript Type	Review
Article Title	Exploring the impact of galectins on liver cancer: From immunopathogenesis to potential targets
Manuscript Source	Invited Manuscript
All Author List	Nevena M Gajovic, Ivan P Jovanovic, Miodrag V Jocic, Bojan Stojanovic, Irfan F Corovic, Nevena Todorovic, Bojana J Simovic Markovic and Amedeo Amedei
Funding Agency and Grant Number
Corresponding Author	Bojana J Simovic Markovic, Center for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovic 69, Kragujevac 34000, Serbia. bojana.simovic@gmail.com
Key Words	Hepatocellular carcinoma; Liver cancer; Galectins; Galectin-3; Galectin-1; Immunopathogenesis; Biomarkers
Core Tip	Hepatocellular carcinoma remains a significant global health challenge characterized by complex molecular and immune-mediated mechanisms. This review provides an in-depth overview of key pathways driving hepatocellular carcinoma pathogenesis, with particular emphasis on the emerging roles of galectins-especially galectin-1 and galectin-3. Their involvement in inflammation, immune regulation, and tumor progression underscores their potential as valuable biomarkers and promising targets for personalized therapeutic strategies.
Citation	Gajovic NM, Jovanovic IP, Jocic MV, Stojanovic B, Corovic IF, Todorovic N, Simovic Markovic BJ, Amedei A. Exploring the impact of galectins on liver cancer: From immunopathogenesis to potential targets. World J Gastroenterol 2025; In press

Received	2025-03-19 10:27
Peer-Review Started	2025-03-19 10:27
To Make the First Decision
Return for Revision	2025-04-08 07:06
Revised	2025-04-19 01:26
Second Decision	2025-06-12 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-12 07:27
Articles in Press	2025-06-12 07:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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