Publication Name	World Journal of Clinical Oncology
Manuscript ID	107271
Country	Egypt

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Clinical significance of the transcription factor (SOX11) expression in the bone marrow of acute myeloid leukemia patients
Manuscript Source	Invited Manuscript
All Author List	Rania S Abdel Aziz, Enas M Radwan, Abdelhamid M Fouad, Mona S Abdellateif and Sally Elfishawy
Funding Agency and Grant Number
Corresponding Author	Mona S Abdellateif, Department of Cancer Biology, National Cancer Institute, Cairo University, 1 Fom Elkhaligue, Cairo 11796, Egypt. mona.sayed@nci.cu.edu.eg
Key Words	Acute myeloid leukemia; SOX11; FLT3; Gene expression; Real-time PCR
Core Tip	Higher SOX11 expression correlated with FAB M2 and abnormal cytogenetics in acute myeloid leukemia (AML) patients. The association of higher SOX11 expression with FLT-ITD mutation could be used for identifying high-risk AML patients who may benefit from targeted or more intensive therapies. Also, the association of higher SOX11 expression with the presence of cytogenetic abnormalities might have implications in predicting risk of translocation development and relapse in patients undertaking high risk therapy.
Citation	Abdel Aziz RS, Radwan EM, Fouad AM, Abdellateif MS, Elfishawy S. Clinical significance of the transcription factor (SOX11) expression in the bone marrow of acute myeloid leukemia patients. World J Clin Oncol 2025; In press

Received	2025-03-20 15:12
Peer-Review Started	2025-03-20 15:12
To Make the First Decision
Return for Revision	2025-04-07 12:20
Revised	2025-04-17 08:56
Second Decision	2025-05-16 02:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-16 09:26
Articles in Press	2025-05-16 09:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
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