Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	107326
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Risk modeling of delayed postoperative bleeding after endoscopic submucosal dissection for early colorectal cancer and precancerous lesions
Manuscript Source	Unsolicited Manuscript
All Author List	Jun Qian, Ya-Li Tao and Shu-Sen Zheng
Funding Agency and Grant Number
Corresponding Author	Shu-Sen Zheng, MD, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. shusenzheng@zju.edu.cn
Key Words	Logistic regression; Early colorectal cancer; Precancerous lesions; Delayed postoperative bleeding; Risk prediction model; Nomogram
Core Tip	Currently, research on risk factors for delayed postoperative bleeding (DPOB) in patients undergoing endoscopic submucosal dissection for early colorectal cancer or precancerous lesions remains limited. This investigation set out to evaluate post-endoscopic submucosal dissection DPOB risk in these patients and to support more informed clinical management by identifying key influencing factors. Multiple lesions, lesions ≥ 3 cm in diameter, rectal lesion location, and marked fibrosis emerged as key independent predictors of DPOB. For patients exhibiting these risk factors, enhanced postoperative surveillance and tailored management strategies are therefore advised to improve their outcomes.
Citation	Qian J, Tao YL, Zheng SS. Risk modeling of delayed postoperative bleeding after endoscopic submucosal dissection for early colorectal cancer and precancerous lesions. World J Gastrointest Surg 2025; In press

Received	2025-05-14 08:47
Peer-Review Started	2025-05-14 08:47
To Make the First Decision
Return for Revision	2025-05-22 09:36
Revised	2025-06-09 14:14
Second Decision	2025-07-25 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-25 06:40
Articles in Press	2025-07-25 06:40
Publication Fee Transferred	2025-06-10 08:48
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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