Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	107347
Country	Russia

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Primary biliary cholangitis: A historical perspective from xanthomatous lesions to modern molecular biology
Manuscript Source	Invited Manuscript
All Author List	Vasiliy Ivanovich Reshetnyak, Elena Vladimirovna Vinnitskaya and Igor Veniaminovich Maev
Funding Agency and Grant Number
Corresponding Author	Vasiliy Ivanovich Reshetnyak, Full Professor, MD, PhD, Department of Propaedeutics of Internal Diseases and Gastroenterology, Russian University of Medicine, No. 20 Delegatskaya Street, Moscow 127473, Russia. vasiliy.reshetnyak@yandex.ru
Key Words	Nonobstructive biliary cirrhosis; Addison-Gull syndrome; La cirrhose hypertrophique avec ictère chronique; Hypertrophic cirrhosis hanot; Xanthomatous biliary cirrhosis; Primary biliary cirrhosis; Primary biliary cholangitis
Core Tip	The present review is devoted to an examination of the historical aspects of primary biliary cholangitis (PBC). The initial references to the disease are examined, along with the evolution of its nomenclature. The importance of the development and the evolution of clinical, laboratory and instrumental methods for the discovery and elucidation of the pathophysiological mechanisms of PBC is shown.
Citation	Reshetnyak VI, Vinnitskaya EV, Maev IV. Primary biliary cholangitis: A historical perspective from xanthomatous lesions to modern molecular biology. World J Gastrointest Pathophysiol 2025; In press

Received	2025-03-25 06:00
Peer-Review Started	2025-03-25 06:01
To Make the First Decision
Return for Revision	2025-04-03 15:30
Revised	2025-04-05 10:54
Second Decision	2025-04-29 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-04-29 08:34
Articles in Press	2025-04-29 08:34
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ISSN	2150-5330 (online)
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