Publication Name	World Journal of Clinical Oncology
Manuscript ID	107438
Country	China

Category	Surgery
Manuscript Type	Minireviews
Article Title	Current status and advances in the treatment of colorectal cancer with liver metastases
Manuscript Source	Invited Manuscript
All Author List	Wei-Xing Liu, Chuang Jiang and Jia-Xin Li
Funding Agency and Grant Number	Funding Agency Grant Number Project of Guizhou Provincial Department of Science and Technology No. Qian Ke He Cheng Guo-LC[2024]109
Corresponding Author	Jia-Xin Li, Assistant Professor, MD, Division of Liver Surgery, Department of General Surgery and Laboratory of Liver Surgery, and State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, West China Hospital, Sichuan University, No. 37 Guo Xue Alley, Chengdu 610041, Sichuan Province, China. lijiaxin@scu.edu.cn
Key Words	Colorectal cancer; Liver metastases; Treatment strategies; Cancer; Review
Core Tip	Colorectal cancer liver metastases (CRLM) present a significant clinical challenge, yet surgical resection of both primary and metastatic lesions can yield favorable outcomes. Advances in systemic therapies enable conversion therapy for initially unresectable cases, offering potential surgical opportunities. However, key controversies persist, including optimal timing of systemic therapy, the role of neoadjuvant treatment, and the choice between simultaneous or staged surgeries. This review outlines current CRLM management strategies and highlights unresolved issues to guide clinical decision-making.
Citation	Liu W, Jiang C, Li JX. Current status and advances in the treatment of colorectal cancer with liver metastases. World J Clin Oncol 2025; In press

Received	2025-03-24 09:35
Peer-Review Started	2025-03-24 09:35
To Make the First Decision
Return for Revision	2025-04-04 15:39
Revised	2025-04-29 16:31
Second Decision	2025-06-23 02:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-23 09:42
Articles in Press	2025-06-23 09:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
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