Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	107573
Country	India

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Fatigue in inflammatory bowel disease: Prevalence, risk factors, assessment, outcomes, and management
Manuscript Source	Invited Manuscript
All Author List	Suprabhat Giri, Sidharth Harindranath, Akshay Kulkarni, Jiten Kumar Sahoo, Harshad Joshi, Preetam Nath and Manoj Kumar Sahu
Funding Agency and Grant Number
Corresponding Author	Preetam Nath, DM, MD, Professor, Department of Gastroenterology and Hepatology, Kalinga Institute of Medical Sciences, Patia, Bhubaneshwar 751024, Odisha, India. drpreetamnath@gmail.com
Key Words	Inflammatory bowel disease; Ulcerative colitis; Crohn’s disease; Fatigue; Gut-Brain axis
Core Tip	Fatigue is a prevalent and debilitating symptom in patients with inflammatory bowel disease (IBD), affecting nearly half of all patients and three-fourths with active disease. Its origins are multifactorial, involving inflammation, nutritional deficiencies, sleep issues, psychological factors, gut microbiota, muscle dysfunction, and inactivity. Identifying and addressing these factors is key to management. The IBD fatigue and functional assessment in chronic illness therapy - fatigue scales are common assessment tools for adults, with PedsQL for pediatric patients. Management involves physical exercise, medical or surgical management of active disease, correcting nutritional deficiencies, and addressing psychological and sleep disorders. Persistent fatigue may require physical and psychological interventions through a multidisciplinary approach.
Citation	Giri S, Harindranath S, Kulkarni A, Sahoo JK, Joshi H, Nath P, Sahu MK. Fatigue in inflammatory bowel disease: Prevalence, risk factors, assessment, outcomes, and management. World J Gastrointest Pathophysiol 2025; In press

Received	2025-03-26 04:02
Peer-Review Started	2025-03-26 04:02
To Make the First Decision
Return for Revision	2025-04-20 09:04
Revised	2025-04-30 00:53
Second Decision	2025-07-03 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-03 08:29
Articles in Press	2025-07-03 08:29
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ISSN	2150-5330 (online)
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