Publication Name	World Journal of Clinical Oncology
Manuscript ID	107660
Country	China

Category	Medicine, Research & Experimental
Manuscript Type	Review
Article Title	Gastrointestinal microbiota in the treatment of gastric precancerous lesions and gastric cancer by western and traditional Chinese medicine
Manuscript Source	Invited Manuscript
All Author List	Ting-Lan Cao and Hui-Zhong Jiang
Funding Agency and Grant Number
Corresponding Author	Hui-Zhong Jiang, PhD, Department of Gastroenterology, Dongzhimen Hospital, Beijing University of Chinese Medicine, No. 11 North Third Ring Road East, Beijing 100700, China. jianghz93@126.com
Key Words	Gastric precancerous lesions; Gastric cancer; Microbiota; Dysbiosis; Western medicine; Traditional Chinese medicine
Core Tip	The development of gastric precancerous lesions (GPL) and gastric cancer (GC) is often driven by Helicobacter pylori infection and is closely linked to changes in the gastrointestinal microbiota. Both Western medicine and traditional Chinese medicine offer therapeutic approaches that modulate the microbiota through various mechanisms, thereby influencing gastric carcinogenesis and treatment outcomes. Consequently, targeting the microbiota represents an encouraging approach for improving the diagnosis, treatment, and overall management of GPL and GC.
Citation	Cao TL, Jiang HZ. Gastrointestinal microbiota in the treatment of gastric precancerous lesions and gastric cancer by western and traditional Chinese medicine. World J Clin Oncol 2025; In press

Received	2025-03-28 04:20
Peer-Review Started	2025-03-28 04:20
To Make the First Decision
Return for Revision	2025-04-16 10:42
Revised	2025-04-26 05:08
Second Decision	2025-06-23 02:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-23 08:25
Articles in Press	2025-06-23 08:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
Open Access	The development of gastric precancerous lesions (GPL) and gastric cancer (GC) is often driven by Helicobacter pylori infection and is closely linked to changes in the gastrointestinal microbiota. Both Western medicine and traditional Chinese medicine offer therapeutic approaches that modulate the microbiota through various mechanisms, thereby influencing gastric carcinogenesis and treatment outcomes. Consequently, targeting the microbiota represents an encouraging approach for improving the diagnosis, treatment, and overall management of GPL and GC.
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com