Publication Name	World Journal of Psychiatry
Manuscript ID	107696
Country	China

Category	Neurosciences
Manuscript Type	Minireviews
Article Title	Interaction between the brain and multiple organ systems in schizophrenia
Manuscript Source	Invited Manuscript
All Author List	Jin Lin, Si-Tong Feng, Zi-Yao Wu, Lin-Rui Dong, Dong-Qing Yin, Hong Zhu, Hong-Xiao Jia and Yan-Zhe Ning
Funding Agency and Grant Number	Funding Agency Grant Number Beijing Traditional Chinese Medicine Scientific and Technological Development Fund Project BJZYYB-2023-66 Beijing Natural Science Foundation 7212050 the Capital’s Funds for Health Improvement and Research 2020-4-2126
Corresponding Author	Yan-Zhe Ning, Beijing Key Laboratory of Mental Disorders, National Medical Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, No. 5 Ankang Hutong, Xicheng District, Beijing 100088, China. ningzy0923@mail.ccmu.edu.cn
Key Words	Schizophrenia; Brain-body interactions; Pathophysiological mechanisms; Multiple organic systems; Systemic integration
Core Tip	While existing reviews of schizophrenia focus primarily on central nervous system pathophysiology, this minireview uniquely highlights the growing evidence of interactions between the brain and peripheral organ systems, including the cardiovascular, pulmonary, hepatic, immune, and renal systems. It underscores the critical role of brain-organ interaction via the autonomic nervous system, endocrine system, and immune system in the pathophysiology of schizophrenia, providing new insights into its underlying mechanisms and potential therapeutic targets.
Citation	Lin J, Feng ST, Wu ZY, Dong LR, Yin DQ, Zhu H, Jia HX, Ning YZ. Interaction between the brain and multiple organ systems in schizophrenia. World J Psychiatry 2025; In press

Received	2025-03-28 04:34
Peer-Review Started	2025-03-31 01:34
To Make the First Decision
Return for Revision	2025-04-08 13:10
Revised	2025-04-19 02:45
Second Decision	2025-06-16 02:50
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-23 10:53
Articles in Press	2025-06-23 10:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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