Publication Name	World Journal of Clinical Cases
Manuscript ID	107716
Country	Colombia

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Retrospective Study
Article Title	Monitoring high-risk patients for chemotherapy-related cardiotoxicity: A retrospective analysis
Manuscript Source	Invited Manuscript
All Author List	Arnold Méndez-Toro, Felipe Alejandro Muñoz-Rossi, Rafael Enrique Tejada-Cabrera, Ingrid Tatiana Rojas-Ruiz, Juan David Flechas-Ardila, Alejandro García-Gutierrez and Ricardo Andrés Novoa-Alvarez
Funding Agency and Grant Number
Corresponding Author	Arnold Méndez-Toro, Professor, Department of Cardiology, Hospital Universitario Nacional de Colombia, Bogota 111321, Bogotá, Colombia. arnold.mendez@hun.edu.co
Key Words	Cardiotoxicity; Antineoplastic Agents/adverse effects; Cardiovascular diseases/chemically induced; Echocardiography; Biomarkers; Drug monitoring
Core Tip	Cardiotoxicity remains a significant concern for cancer patients undergoing high-risk chemotherapy. This study, conducted at the National University Hospital of Colombia, highlights the importance of echocardiography and biomarkers in detecting chemotherapy-induced cardiac damage. Among 195 patients analyzed, 8.7% developed cardiotoxicity, with significant declines in left ventricular ejection fraction and longitudinal strain. While biomarker usage showed variability, their potential for early detection is evident. The results underscore the critical need for standardized protocols to enhance early detection and management of cardiotoxicity, enabling timely interventions and improved patient outcomes. This study advances the understanding of cardiotoxicity risk and management, advocating for structured multidisciplinary programs to optimize care.
Citation	Méndez-Toro A, Muñoz-Rossi FA, Tejada-Cabrera RE, Rojas-Ruiz IT, Flechas-Ardila JD, García-Gutierrez A, Novoa-Alvarez RA. Monitoring high-risk patients for chemotherapy-related cardiotoxicity: A retrospective analysis. World J Clin Cases 2025; In press

Received	2025-04-01 13:51
Peer-Review Started	2025-04-01 13:52
To Make the First Decision
Return for Revision	2025-04-14 10:03
Revised	2025-04-25 20:19
Second Decision	2025-06-13 02:50
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-13 08:24
Articles in Press	2025-06-13 08:24
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ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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