Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	107804
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Preoperative computed tomography-based risk stratification model validation for postoperative pancreatic ductal adenocarcinoma recurrence
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Hui Liu, Jing-Hong Xie, Xi-Song Zhu and Li-Heng Liu
Funding Agency and Grant Number
Corresponding Author	Li-Heng Liu, Associate Chief Physician, MD, Department of Radiology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Xuhui District, Shanghai 200000, China. liu.liheng@zs-hospital.sh.cn
Key Words	Pancreatic ductal adenocarcinoma; Postoperative recurrence; Risk assessment system; Computed tomography; Model validation
Core Tip	This multinational study externally validated a preoperative computed tomography-based risk model, originally developed in South Korea, for predicting recurrence-free survival (RFS) in patients with pancreatic ductal adenocarcinoma (PDAC), after surgery. Analyzing 283 patients from a distinct population, the model-incorporating tumor size, portal venous phase density, necrosis, peripancreatic infiltration, and metastatic lymph nodes-stratified patients into prognostic groups. The good prognosis group exhibited significantly longer RFS despite a 76% overall recurrence rate. The findings confirm its cross-population applicability, supporting its use as a preoperative tool to identify patients at high risk of PDAC and guide clinical decision-making.
Citation	Liu XH, Xie JH, Zhu XS, Liu LH. Preoperative computed tomography-based risk stratification model validation for postoperative pancreatic ductal adenocarcinoma recurrence. World J Gastrointest Surg 2025; In press

Received	2025-03-30 05:45
Peer-Review Started	2025-03-30 05:45
To Make the First Decision
Return for Revision	2025-04-09 15:37
Revised	2025-04-16 03:32
Second Decision	2025-05-20 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-20 03:39
Articles in Press	2025-05-20 03:39
Publication Fee Transferred	2025-04-18 03:07
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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