Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	107815
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Correlation of radiotherapy, targeted therapy, and immunotherapy with hepatocellular carcinoma recurrence
Manuscript Source	Invited Manuscript
All Author List	Qian-Jia Liu, Jia-Cheng Zhang, Yue-Fan Wang, Ming-Hao Zou, Wen-Xuan Zhou, Yan Lu, Xiao-Chen Feng and Hui Liu
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China No. 82270634 Third Affiliated Hospital of Naval Medical University No. tf2024yzyy01
Corresponding Author	Hui Liu, The Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, No. 225 Changhai Road, Shanghai 200082, China. liuhuigg@hotmail.com
Key Words	Hepatocellular carcinoma; Tumor recurrence; Radiotherapy; Targeted Therapy; Immunotherapy; Treatment strategies
Core Tip	Hepatocellular carcinoma (HCC) is a prevalent cancer worldwide, ranking as the third leading cause of cancer-related deaths. Despite advancements in treatment modalities, a significant proportion of patients with HCC (50%-70%) experience tumor recurrence within 5 years of initial treatment. This review focuses on the roles of radiotherapy, targeted therapy, and immunotherapy in managing post-surgical HCC recurrence and their combined effects.
Citation	Liu QJ, Zhang JC, Wang YF, Zou MH, Zhou WX, Lu Y, Feng XC, Liu H. Correlation of radiotherapy, targeted therapy, and immunotherapy with hepatocellular carcinoma recurrence. World J Gastrointest Oncol 2025; In press

Received	2025-04-01 15:06
Peer-Review Started	2025-04-01 15:06
To Make the First Decision
Return for Revision	2025-04-16 10:22
Revised	2025-04-30 16:11
Second Decision	2025-06-19 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-19 06:32
Articles in Press	2025-06-19 06:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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