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Publication Name World Journal of Meta-Analysis
Manuscript ID 107997
Country India
Category Biochemistry & Molecular Biology
Manuscript Type Systematic Reviews
Article Title Liquid biopsy in hepatobiliary and pancreatic cancers: A paradigm shift in early detection, prognostic stratification, and perioperative monitoring
Manuscript Source Invited Manuscript
All Author List Himanshu Agrawal, Binita Goswami, Nikhil Gupta and Nilanjana Singh
Funding Agency and Grant Number
Corresponding Author Nikhil Gupta, FACS, FRCS (Gen Surg), Professor, Department of Surgery, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, BKS Marg, Delhi 110001, India. nikhil_ms26@yahoo.co.in
Key Words Liquid biopsy; Circulating tumor DNA; Hepatobiliary cancer; Pancreatic cancer; Perioperative monitoring
Core Tip Liquid biopsy is a minimally invasive technique that detects circulating tumor DNA, circulating tumor cells, and other biomarkers in bodily fluids. It offers real-time monitoring of tumor dynamics, treatment response, and minimal residual disease. Unlike traditional tissue biopsies, liquid biopsy allows for repeated sampling, providing insights into tumor heterogeneity and evolution. It has applications in early cancer detection, prognosis, and guiding targeted therapies. Despite its advantages, challenges such as standardization, sensitivity, and specificity remain. Further research and technological advancements are needed to enhance its clinical utility.
Citation Agrawal H, Goswami B, Gupta N, Singh N. Liquid biopsy in hepatobiliary and pancreatic cancers: A paradigm shift in early detection, prognostic stratification, and perioperative monitoring. World J Meta-Anal 2025; In press
Received
2025-04-02 08:24
Peer-Review Started
2025-04-02 09:04
To Make the First Decision
Return for Revision
2025-04-10 09:22
Revised
2025-04-10 10:47
Second Decision
2025-05-08 02:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-05-08 13:03
Articles in Press
2025-05-08 13:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2308-3840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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