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Publication Name World Journal of Clinical Oncology
Manuscript ID 108113
Country United States
Category Oncology
Manuscript Type Retrospective Cohort Study
Article Title Vitamin D deficiency in prostate cancer: Prevalence in a sun-rich climate and influence of androgen deprivation therapy
Manuscript Source Unsolicited Manuscript
All Author List Nazmul Hasan, Desiree Rafizadeh, Spencer Gibson, Dalia Kaakour, Benjamin Lee, Barbod Khaleghi, Omid Yazdanpanah and Arash Rezazadeh Kalebasty
Funding Agency and Grant Number
Corresponding Author Nazmul Hasan, MD, Department of Medicine, University of California, Irvine, 333 City Blvd W, Suite 400, Orange, CA 92868, United States. nhasan1@hs.uci.edu
Key Words Metastatic prostate cancer; Sunlight exposure; Bone health; Racial disparities; Androgen deprivation therapy; Prostate cancer; Vitamin D
Core Tip This retrospective study investigates the prevalence of vitamin D deficiency in prostate cancer patients who received treatment in Southern California, a region characterized by high annual sun exposure. It underscores the high deficiency rates among advanced-stage disease patients, as well as Hispanic and Black patients. The study also assesses the impact of androgen deprivation therapy on vitamin D and concludes that there is no substantial change in response to treatment. These results provide evidence for routine screening and supplementation of vitamin D, particularly in high-risk subgroups, and challenges the notion that sun exposure alone guarantees adequate vitamin D levels.
Citation Hasan N, Rafizadeh D, Gibson S, Kaakour D, Lee B, Khaleghi B, Yazdanpanah O, Rezazadeh Kalebasty A. Vitamin D deficiency in prostate cancer: Prevalence in a sun-rich climate and influence of androgen deprivation therapy. World J Clin Oncol 2025; In press
Received
2025-04-07 06:51
Peer-Review Started
2025-04-07 06:51
To Make the First Decision
Return for Revision
2025-04-17 11:01
Revised
2025-04-22 06:47
Second Decision
2025-05-15 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-05-15 08:57
Articles in Press
2025-05-15 08:57
Publication Fee Transferred
2025-04-24 18:29
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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