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Articles in Press
6/20/2025 6:50:05 AM | Browse: 29 | Download: 0
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Letter to the Editor |
Article Title |
Adjuvant chemotherapy for gallbladder cancer: Current evidence, controversies, and future directions
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Jin-Wei Dai, Yi-Xuan Xing and Nian-Zhe Sun |
Funding Agency and Grant Number |
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Corresponding Author |
Nian-Zhe Sun, MD, PhD, Department of Orthopedics, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Kaifu District, Changsha 410008, Hunan Province, China. sunnzh201921@sina.com |
Key Words |
Gallbladder cancer; Adjuvant chemotherapy; National Cancer Database; Retrospective analysis; Cancer staging |
Core Tip |
Whether patients with stage II gallbladder cancer should routinely receive adjuvant chemotherapy after surgery remains uncertain. The analysis by Kim et al, based on National Cancer Database data, found no statistically significant survival benefit associated with chemotherapy in these patients. However, the results should not be hastily interpreted as evidence against chemotherapy altogether. Instead, clinicians must consider individualized treatment decisions based on pathological features and the patient’s overall health condition. This article further evaluated the strengths and weaknesses of Kim et al’s research design. It recommended conducting future studies, ideally prospective clinical trials or refined retrospective analyses, to better clarify chemotherapy’s role in this context. |
Citation |
Dai JW, Xing YX, Sun NZ. Adjuvant chemotherapy for gallbladder cancer: Current evidence, controversies, and future directions. World J Gastrointest Surg 2025; In press |
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Received |
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2025-04-07 04:35 |
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Peer-Review Started |
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2025-04-07 04:35 |
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To Make the First Decision |
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Return for Revision |
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2025-04-17 10:41 |
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Revised |
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2025-04-24 13:57 |
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Second Decision |
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2025-06-20 02:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-06-20 06:50 |
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Articles in Press |
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2025-06-20 06:50 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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ISSN |
1948-9366 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
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