Publication Name	World Journal of Stem Cells
Manuscript ID	108202
Country	Kazakhstan

Category	Endocrinology & Metabolism
Manuscript Type	Meta-Analysis
Article Title	Autologous and allogeneic mesenchymal stem cell-based therapies for diabetes mellitus: A systematic review and meta-analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Raisa A Aringazina, Afshin Zare, Seyyed Mojtaba Mousavi, Nurgul Abenova, Nadiar Maratovich Mussin and Amin Tamadon
Funding Agency and Grant Number	Funding Agency Grant Number Clinical Variants of Metabolic Syndrome and Hormonal Mechanisms of its Formation in the Residents of Aktobe City 8/5-1-04/1-36/1
Corresponding Author	Amin Tamadon, Full Professor, PhD, Department of Natural Sciences, West Kazakhstan Marat Ospanov Medical University, No. 60 Maresiev Street, Aktobe 030012, Kazakhstan. amintamaddon@yahoo.com
Key Words	Type 2 diabetes mellitus; Metabolic disorders; Obesity; Insulin lessen; Insulin resistance; Cell therapy; Mesenchymal stem cell
Core Tip	This comprehensive review explores the potential of mesenchymal stem cell (MSC)-based therapies, both autologous and allogeneic, for treating type 2 diabetes mellitus. The study evaluates the safety, efficacy, and therapeutic benefits of MSCs, highlighting improvements in glycemic control, reductions in insulin requirements, and enhanced β-cell function. While MSC-based therapies show promising results with minimal adverse effects, challenges remain in standardizing treatment protocols. Future research should aim to refine these therapies and assess their long-term effects through large-scale clinical trials.
Citation	Raisa A Aringazina, Afshin Zare, Seyyed Mojtaba Mousavi, Nurgul Abenova, Nadiar Maratovich Mussin, Amin Tamadon. Autologous and allogeneic mesenchymal stem cell-based therapies for diabetes mellitus: A systematic review and meta-analysis. World J Stem Cells 2025; In press

Received	2025-04-08 13:19
Peer-Review Started	2025-04-08 13:19
To Make the First Decision
Return for Revision	2025-04-23 11:47
Revised	2025-05-01 06:11
Second Decision	2025-06-26 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-03 07:37
Articles in Press	2025-07-03 07:37
Publication Fee Transferred	2025-05-08 05:55
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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