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Publication Name World Journal of Gastroenterology
Manuscript ID 108271
Country Mexico
Category Gastroenterology & Hepatology
Manuscript Type Letter to the Editor
Article Title Phospholipase D2: A biomarker implicated in various pancreatic diseases beyond acute pancreatitis
Manuscript Source Invited Manuscript
All Author List Ana I Tornel Avelar, Christian Navarro Gerrard and Bryan Adrian Priego Parra
Funding Agency and Grant Number
Funding Agency Grant Number
Mexican Association of Gastroenterology 2023 for the scholarship warded
Corresponding Author Bryan Adrian Priego Parra, MD, PhD, Department of Digestive Physiology and Gastrointestinal Motility, Institute of Medical-Biological Research, Universidad Veracruzana, Iturbide S/N Entre Carmen Serdán y 20 de Noviembre, Col. Flores Magón, Veracruz 91700, Veracruz, Mexico. bryanpriegop@gmail.com
Key Words Phospholipase D2; Acute pancreatitis; Chronic pancreatitis; Pancreatic Biomarkers; Pancreatic cancer; Sexual dimorphism
Core Tip Phospholipase D2 is a key enzyme involved in the hydrolysis of phospholipids. It has been implicated in processes, such as neutrophil migration, the inflammatory response, apoptosis, cell migration, and adhesion in various pathologies. This letter to the editor analyzes multiple research sources on phospholipase D2 in pancreatic conditions, including acute pancreatitis, chronic pancreatitis, and pancreatic cancer. It also highlights the need for future research to consider sex differences in the expression of this enzyme and to evaluate its applicability in clinical practice.
Citation Tornel Avelar AI, Gerrard CN, Priego Parra BA. Phospholipase D2: A biomarker implicated in various pancreatic diseases beyond acute pancreatitis. World J Gastroenterol 2025; In press
Received
2025-04-09 10:11
Peer-Review Started
2025-04-09 10:12
To Make the First Decision
Return for Revision
2025-05-10 19:00
Revised
2025-05-24 02:32
Second Decision
2025-07-04 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-07-04 07:21
Articles in Press
2025-07-04 07:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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