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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 108274
Country China
Category Oncology
Manuscript Type Basic Study
Article Title BTNL9 exerts anti-cancer effects by inhibiting CDC20 to induce G2/M arrest in pancreatic cancer
Manuscript Source Unsolicited Manuscript
All Author List Mao Xiao, Zhi-Yan Luo, Ai-Ru Yu, Ke Xu and Wei Zhou
Funding Agency and Grant Number
Funding Agency Grant Number
Sichuan Medical Association Research Project Q2024049
Clinical Science Research Fund of Chengdu Medical College 24 LHLNYX1-03
Chengdu Medical College Elite Peak Program 2024qnGzn04
Key Clinical Specialty of Sichuan Province YS00109
Corresponding Author Wei Zhou, Department of Radiology, The First Affiliated Hospital of Chengdu Medical College, <label>6</label><institution-wrap><institution-id institution-id-type="GRID">grid.413856.d</institution-id><institution-id institution-id-type="ISNI">0000 0004 1799 3643</institution-id><institution>Clinical Medical College, </institution><institution>Chengdu Medical College, </institution></institution-wrap>Chengdu, Sichuan China, Chengdu 610500, Sichuan Province, China. zhouwei@cmc.edu.cn
Key Words Pancreatic cancer; Butyrophilin like 9; Cell division cycle 20; Cell cycle; Prognosis
Core Tip The present study reported the down-regulated expression of BTNL9 in pancreatic cancer (PC), which correlated with a poorer prognosis. PC cells overexpressing BTNL9 exhibited cell cycle arrest at the G2/M, accompanied by a reduction in their proliferative and metastatic capacity. BTNL9 regulates the cell cycle by inhibiting cell division cycle 20.
Citation Xiao M, Luo ZY, Yu AR, Xu K, Zhou W. BTNL9 exerts anti-cancer effects by inhibiting CDC20 to induce G2/M arrest in pancreatic cancer. World J Gastrointest Oncol 2025; In press
Received
2025-04-10 01:39
Peer-Review Started
2025-04-10 01:39
To Make the First Decision
Return for Revision
2025-04-22 12:24
Revised
2025-05-01 05:12
Second Decision
2025-05-29 02:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-05-29 07:24
Articles in Press
2025-05-29 07:24
Publication Fee Transferred
2025-05-07 04:59
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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