Publication Name	World Journal of Methodology
Manuscript ID	108291
Country	India

Category	Ophthalmology
Manuscript Type	Retrospective Study
Article Title	Is elevated serum homocysteine in isolated ischemic cranial nerve palsies a predictor of stroke?
Manuscript Source	Invited Manuscript
All Author List	Pallikkara Divya Ravindran, Sharanya Rajendra, Karthik Kumar and Virna M Shah
Funding Agency and Grant Number
Corresponding Author	Virna M Shah, Chief Physician, Department of Neuro Ophtalmology, Aravind Eye Hospital, Tamilnadu, Coimbatore 641014, Tamil Nādu, India. virna@aravind.org
Key Words	Cranial nerve palsy; Homocysteine; Stroke; Ischemia
Core Tip	This retrospective study of 66 patients with isolated ischemic cranial nerve palsies found elevated serum homocysteine in over half the cases, including those without traditional vascular risk factors. The findings suggest homocysteine may be an independent risk factor for stroke, supporting routine testing in such patients which may help identify stroke risk early and guide preventive care.
Citation	Ravindran PD, Ravindra S, Kumar K, Shah VM. Is elevated serum homocysteine in isolated ischemic cranial nerve palsies a predictor of stroke? World J Methodol 2025; In press

Received	2025-04-11 09:12
Peer-Review Started	2025-04-22 09:06
To Make the First Decision
Return for Revision	2025-05-09 12:29
Revised	2025-05-21 04:15
Second Decision	2025-08-07 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-08-08 09:51
Articles in Press	2025-08-08 09:51
Publication Fee Transferred
Edit the Manuscript by Language Editor	2025-08-12 21:14
Typeset the Manuscript

ISSN	2222-0682 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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