Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	108345
Country	Singapore

Category	Surgery
Manuscript Type	Retrospective Study
Article Title	Postoperative outcomes following prehabilitation vs no prehabilitation in elective colorectal surgery: A 2:1 propensity score-matched analysis
Manuscript Source	Invited Manuscript
All Author List	Kai Siang Chan, Priscilla Ng, Lynn Tan, Rachel E-Jing Soh, Boon Theng Tan, Yu Jing Ong, Joon Lan Chong, Surendra Kumar Mantoo, Yao Zong Lee, Kok-Yang Tan and Daniel Jin Keat Lee
Funding Agency and Grant Number
Corresponding Author	Kai Siang Chan, Researcher, Department of General Surgery, Khoo Teck Puat Hospital, No. 90 Yishun Central, Singapore 768828, Singapore. kchan023@e.ntu.edu.sg
Key Words	Colorectal surgery; Elderly; Enhanced recovery after surgery; Frailty; Hemicolectomy; Prehabilitation
Core Tip	Ageing is associated with frailty, increased co-morbidities and worse post-operative outcomes. Some studies on prehabilitation showed its potential in improving post-operative outcomes for elective colorectal surgery but selection criteria and prehabilitation protocols are heterogeneous. Through propensity score matching, this study showed that prehabilitation in non-frail older patients (≥ 65 years) did not improve short-term outcomes and 1-year mortality. Open surgery was an independent predictor of 1-year mortality. Consideration should be made to modify and stratify the selection criteria for prehabilitation based on frailty scores and co-morbidity burden to identify the group of patients who will best benefit given finite resources.
Citation	Chan KS, Ng P, Tan L, Soh REJ, Tan BT, Ong YJ, Chong JL, Mantoo SK, Lee YZ, Tan KY, Lee DJK. Postoperative outcomes following prehabilitation vs no prehabilitation in elective colorectal surgery: A 2:1 propensity score-matched analysis. World J Gastrointest Surg 2025; In press

Received	2025-04-14 03:42
Peer-Review Started	2025-04-14 03:42
To Make the First Decision
Return for Revision	2025-05-21 21:21
Revised	2025-06-20 02:51
Second Decision	2025-09-19 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-19 03:58
Articles in Press	2025-09-19 03:58
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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