Publication Name	World Journal of Clinical Cases
Manuscript ID	108411
Country	China

Category	Dentistry, Oral Surgery & Medicine
Manuscript Type	Letter to the Editor
Article Title	Low salivary uric acid levels and periodontitis: New insights and implications for clinical practice
Manuscript Source	Invited Manuscript
All Author List	Zhuo-Qun Hu and Yong Wang
Funding Agency and Grant Number
Corresponding Author	Yong Wang, Researcher, Department of Internal Medicine, Yanbian University Hospital, No. 1327 Ju Zi Road, Yanji 133000, Jilin Province, China. wangyong0327ybu@163.com
Key Words	Clinical practice; Biomarker; Oxidative stress; Periodontitis; Salivary uric acid
Core Tip	This letter explores the relationship between low salivary uric acid levels and periodontitis, revealing a significant independent association and inverse correlation with disease severity. Salivary uric acid emerges as a potential biomarker for disease progression, offering new insights into the pathophysiology of periodontitis and paving the way for innovative diagnostic and therapeutic strategies in clinical practice.
Citation	Hu ZQ, Wang Y. Low salivary uric acid levels and periodontitis: New insights and implications for clinical practice. World J Clin Cases 2025; In press

Received	2025-04-14 04:15
Peer-Review Started	2025-04-14 04:15
To Make the First Decision
Return for Revision	2025-05-15 00:28
Revised	2025-05-23 10:46
Second Decision	2025-07-21 03:00
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-22 01:12
Articles in Press	2025-07-22 01:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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